A comparision of lymphocyte/monocyte ratio with meld and child- pugh scores in patients with liver cirrhosis
Vikas N, Nischitha P, Ramrajesh, Kavya S T
Background: To develop an easy and reliable score for evaluating the prognosis of patients with liver cirrhosis has always been challenging. LMR is readily available indictor for predicting the prognosis in cirrhosis of liver. This study was undertaken to examine the association of LMR with the MELD and Child Pugh score.Material and Methods: This study was undertaken in a tertiary care hospital including 30 patients suffering with cirrhosis of liver. Lymphocyte and monocyte counts were obtained from complete blood count results by using standard automated analyzer and LMR was calculated by dividing the lymphocyte count with the monocyte count. Liver failure severity on admission was assessed using the MELD and Child – Pugh scores.Results: Mean LMR was 2.8, MELD score was 80.13 and CP scores was 11.03 in all the patients in this study. The ROC curve had shown that, LMR had a statistically significant AOC for predicting the prognosis of the disease. The lymphocyte count, serum albumin were higher in the patients with high LMR. Age, monocyte count, serum creatinine, MELD scores and Child Pugh scores were higher in the low LMR group. About 87.5% of the patients with low LMR and 66.7% of the patients with high LMR were categorized as C according to Child Pugh scores.Conclusion: The LMR can be used as an independent predictor in assessing the prognosis of patients with liver cirrhosis.
Vikas N, Nischitha P, Ramrajesh, Kavya S T. A comparision of lymphocyte/monocyte ratio with meld and child- pugh scores in patients with liver cirrhosis. International Journal of Medicine Research, Volume 6, Issue 3, 2021, Pages 18-21