International Journal of Medicine Research

International Journal of Medicine Research


International Journal of Medicine Research
International Journal of Medicine Research
Vol. 6, Issue 2 (2021)

A study on correlation between mean platelet volume and severiy of acute ischemic stroke in diabetes mellitus


Gajendra Dewangan, Devpriya Lakra, Manisha Khande

Background: Strokes are broadly classified as ischemic or haemorrhagic. Ischemic stroke is due to occlusion of cerebral blood vessel and causes cerebral infarction. About 85 % of all first ever strokes are ischemic, 10 % are due to primary intracerebral haemorrhage and about 5 % are due to subarachnoid haemorrhage. The majority (about 80%) of stroke is ischemic; the remainder result from primary hemorrhage either intracerebral or into the subarachnoid space. Diabetes mellitus is well established independent risk factor of stroke. Under some pathological conditions like diabetes mellitus, obesity, metabolic syndrome, acute myocardial infarction (AMI), and stroke, the platelets may be larger in size and more reactive and this phenomenon seems to play an important role in several vascular diseases. Mean platelet volume (MPV) could be obtained from a simple and routine blood count and has a prognostic significance in stroke and AMI. It is well documented that there is a direct relationship between the platelet physiology and ischemic stroke by a number of observations. So the present study was planned in order to assess the correlation between mean platelet volume and severity of acute ischemic stroke in patient of Diabetes mellitus. Materials and methods: The present study was a Hospital based, observational, cross sectional study carried out from September 2018 to August 2019, In pt jnm medical college Raipur Chhattisgarh on 40 cases satisfying the inclusion criteria following complete assessment. Patients were assessed for acute ischemic stroke with diabetes mellitus attending medicine OPD or casualty and admitted in medicine ward. Result: Evaluation done on the basis of complete blood count, fasting blood sugar, post prandial blood sugar, lipid profile, Hb1AC, NCCT of head and BMI Conclusion: This study has shown an elevation of MPV in diabetes mellitus is associated with increased severity of acute ischemic stroke. Thus, increase in MPV is independently associated with severity of acute ischemic stroke. There is significant association between NIHSS and outcome of stroke in our study. Also, the MPV estimation test considered a simple, cost-effective and meaningful laboratory markers test for early detection and risk stratification of cerebrovascular stroke.
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How to cite this article:
Gajendra Dewangan, Devpriya Lakra, Manisha Khande. A study on correlation between mean platelet volume and severiy of acute ischemic stroke in diabetes mellitus. International Journal of Medicine Research, Volume 6, Issue 2, 2021, Pages 23-28
International Journal of Medicine Research International Journal of Medicine Research