International Journal of Medicine Research

Authors
Dhanakar Thakur, Binod Kumar Ravi

Abstract
Background and objectives: Plasmodium transmitted by infected female Anopheles mosquitoes, causing malaria, and anemia is observed; however, we found thrombocytopenia also as an unusual accompaniment in many cases. Platelet count was also evaluated for assessing severity of the infection to correlate it in P. vivax and P. falciparum cases and to determine the severity of the disease with its level. Method: The study was conducted in 252 febrile patients seen between August 26^th 2018 to September 16^th 2018 in the camp organized by the Rajshree Medical Research Institute (RMRI) Bareilly on the bank of Ramganga River. Total Platelet count was analyzed in various species of malaria positive patients. Autopsy were also done in two cases. Results: In this study, 198 (78.57%) were positive for Plasmodium vivax, 40 (15.88%) were positive for P. falciparum and 14 (5.55%) had mixed infection. Majority were having thrombocytopenia. Severe thrombocytopenia cases were found in severe state of disease. Signs of bleeding and clotting disorders were seen in autopsy. Interpretation and conclusion: Thrombocytopenia in patients of acute malaria is not so uncommon, however, platelet count has not been given due attention. This study can have therapeutic implications of avoiding unnecessary platelet infusion in malaria patients with relatively not too lower level of thrombocytopenia.