International Journal of Medicine Research

Authors
Dr. Pradeep Prajapati, Dr. Mukesh Singh Tomar, Dr. Rajkishori Prajapati

Abstract
Background: Patients with chronic obstructive pulmonary disease (COPD) and chronic kidney disease (CKD) share common risk factors. However, limited evidence is available about the association between COPD and CKD. Aims and Objectives: To study the clinical profile, frequency of abnormal renal parameters and outcome in patients with COPD. Materials and Methods: Hundred COPD patients attending OPD and in wards of JA Group of Hospitals, G.R. Medical College, Gwalior between September 2016 and August 2018 were studied. Based on FEV1 value, COPD was characterized in Mild, Moderate, Severe and Very Severe. Urine R/M, blood urea, serum creatinine, serum albumin, serum sodium, serum potassium, creatinine clearance and USG abdomen were performed. Results: COPD was more prevalent in males (75%) with age groups of 60 to 70 years (45%) and who were chronic smokers. Majority of the patients had very severe COPD (43%). Anaemia was more prevalent among female population (20 out of 25), 59% of anemic patients had creatinine clearance of <60. Renal failure was more prevalent in male population (36%). Hyponatremia was more common in female (44%). Majority of the hyponatremia patients had very severe COPD (25 out of 41). Hypoalbuminemia was more common among male patients (37%), in the age group of 60-70 years. Pedal Edema was present in 21% patients and was more common in very severe COPD group (15 out of 21). Conclusion: Hyponatremia, deranged renal functions and their magnitude can be an important prognostic tool in patients with COPD as well.