International Journal of Medicine Research

International Journal of Medicine Research


International Journal of Medicine Research
International Journal of Medicine Research
Vol. 3, Issue 2 (2018)

Dysnatremia in cardiac failure


Dr. Aeshal M Parmar, Dr. Rupal V Dosi, Dr. R Raghapriya

Background: Heart failure is rapidly increasing problem worldwide. Despite recent advances, the development of symptomatic heart failure carries poor prognosis. The sodium concentration affects three dimensional structure of proteins and enzymesand thus play a critical role in maintaining electrical gradient across cellular membrane in muscular excitation. Small changes in sodium concentration may have deleterious effect on cardiac muscle function in patients with heart failure. Aims: The aims of study were 1. To measure serum sodium level in patients with heart failure and to classify whether patient is having eunatremia or dysnatremia. 2. To correlate serum sodium level with left ventricular ejection fraction (LVEF), systolic blood pressure (SBP), blood urea and serum creatinine level. Material and Methods: The study included 88 patients with heart failure of any cause admitted to SSG Hospital. And the study was cross sectional analytical. Results: Out of 88 patients, 44 had eunatremia, 41 had hyponatremia and 3 had hypernatremia. The patients with eunatremia had higher LVEF and SBP than patients with dysnatremia. The patients with hyponatremia had higher S. creatinine level than patients with eunatremia or hyponatremia. The patients with hypernatremia had higher blood urea level than patients with eunatremia or hyponatremia. Conclusion: Dysnatremia is a common occurrence in heart failure. The eunatremia is associated with higher LVEF, higher SBP, lower blood urea and lower S. creatine level. The hyponatremia is associated with lower LVEF, lower SBP, higher S. creatinine and higher blood urea level. The hypernatremia is associated with higher LVEF, lower SBP, higher blood urea and lower S. creatinine level.
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How to cite this article:
Dr. Aeshal M Parmar, Dr. Rupal V Dosi, Dr. R Raghapriya. Dysnatremia in cardiac failure. International Journal of Medicine Research, Volume 3, Issue 2, 2018, Pages 93-96
International Journal of Medicine Research International Journal of Medicine Research