International Journal of Medicine Research

International Journal of Medicine Research


International Journal of Medicine Research
International Journal of Medicine Research
Vol. 3, Issue 1 (2018)

Comparative study of caudal bupivacaine and caudal bupivacaine-midazolam combination in paediatric patients for post-operative analgesia


Dr. Manish Banjare, Dr. Basant Kumar Ningawal, Dr. Shailendra Singh, Dr. KK Arora

Context: Single-shot caudal anaesthesia with local anaesthetics (bupivacaine) is the most commonly used regional technique for intraoperative and postoperative pain relief in children as it is safe, reliable and provides efficient analgesia but it has only a short duration of action. The present study has been carried out to evaluate the efficacy of caudal bupivacaine and caudal bupivacaine and midazolam for post operative analgesia in paediatric patients.
Aims and Objectives: To compare the effects of addition of midazolam to 0.25% bupivacaine on the duration of analgesia produced by caudal block and evaluate side effects if any.
Study Design: The study was a prospective, randomized, comparative study.
Materials and Methods: 50 patients with ASA grade 1, of age group 1 to 10 years, scheduled for elective unilateral inguinal herniotomy and urogenital surgeries are grouped into Group 1 that received caudal block with bupivacaine (0.25%) 1 ml/kg and Group 2 that received caudal block with bupivacaine (0.25%) 1 ml/kg with midazolam (50 microgram/kg) as additive.
Statistical analysis used: Data were analysed by analysis of variance with Fisher’s exact test for nominal data. A value of P<0.05 was regarded as statistically significant.
Results: Onset of pain was faster in group 1. After eight postoperative hour observer pain score (OPS) showed statistically significant increase in values for Group 1 as compared to Group 2.
Conclusion: Addition of midazolam to caudal bupivacaine prolongs the duration of post operative analgesia and is remarkably safe.
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How to cite this article:
Dr. Manish Banjare, Dr. Basant Kumar Ningawal, Dr. Shailendra Singh, Dr. KK Arora. Comparative study of caudal bupivacaine and caudal bupivacaine-midazolam combination in paediatric patients for post-operative analgesia. International Journal of Medicine Research, Volume 3, Issue 1, 2018, Pages 82-84
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