International Journal of Medicine Research

International Journal of Medicine Research


International Journal of Medicine Research
International Journal of Medicine Research
Vol. 2, Issue 5 (2017)

Acute and transient psychotic disorder and schizophrenia: On a continuum or distinct? A study of cognitive functions


Dr. Loya Mitali, Dr. Dubey Vaibhav, Dr. Diwan Sanjeet, Dr. Singh Himanshu, Dr. Tiwari Apurva, Dr. Khan Sumera

Background: The overview of epidemiology of acute and transient psychotic disorder (ATPD) shows that it is wrong to assume that ATPD is somehow rudimentary or attenuated form of schizophrenia. This explorative study was designed to ascertain if there are any cognitive function differences between ATPD and cases of first episode schizophrenia (FES). Aims and objective: To study the cognitive functions in the cases of ATPD and FES. Materials and Methods: Cognitive functions of 60 patients (30 patients with ATPD and 30 FES patients) were studied using various tests from National Institute of Mental Health and Neurosciences (NIMHANS) neuropsychological battery. Assessment of the level of cognitive impairment was done using cut off scores of NIMHANS neuropsychological battery. Prevalence of cognitive impairment and comparison of mean scores on different parameters of tests was studied using chi square and student t test using SPSS Ver. 20 software. P value of <0.05 is considered as significant. Results: In terms of cognitive function both the groups were comparable. Prevalence of cognitive impairment was significantly more in FES group only in the domains of sustained attention (p=0.028) and visuospatial working memory (p<0.05). Mean score of DVT errors (p=0.002), DVT time (p=0.005), N Back1 Visual Errors (P=0.02) and N Back2 Visual Errors (P=0.001) were significantly high in FES group whereas N Back 1 Visual Hits score (P=0.003) was significantly high in ATPD group. Conclusions: Both the groups were comparable in cognition impairment; this supports the hypothesis of both the disorders lying on the same continuum.
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How to cite this article:
Dr. Loya Mitali, Dr. Dubey Vaibhav, Dr. Diwan Sanjeet, Dr. Singh Himanshu, Dr. Tiwari Apurva, Dr. Khan Sumera. Acute and transient psychotic disorder and schizophrenia: On a continuum or distinct? A study of cognitive functions. International Journal of Medicine Research, Volume 2, Issue 5, 2017, Pages 04-07
International Journal of Medicine Research International Journal of Medicine Research