International Journal of Medicine Research

International Journal of Medicine Research


International Journal of Medicine Research
Vol. 2, Issue 2 (2017)

Protective effect of royal jelly on the sperm parameters in adult mice treated with lithium carbonate


Nasir A Ibrahim, Mohamed S Alessia, Mohamed YA Babiker, Abdulkhalig Babiker, Hozifa S Yousif

In the current study, was assessed the protective effects of royal jelly on sperm parameters, adult mice treated with lithium carbonate. Adult male albino mice with a mean weight of 25±2 g were divided into two experimental groups and one control group, each with ten mice. The first experimental group was treated with 75 mg/kg doses of lithium carbonate lithium which was taken by injection intraperitoneal for a 20 day of spermatogenesis process. In each gavage, 0.5 mL of lithium carbonate was given to the mice. The second experimental group was treated with 75 mg/kg doses of lithium carbonate lithium which was taken by injection pm and Royal Jelly (RJ) received dose of 250 mg/kg daily for 20 days orally. The result shows that lithium carbonate caused significant changes at level (P≤ 0.05) in total sperm count as compared to control. However, lithium carbonate plus RJ treatment were insignificant in total sperm count as compared to control. In group treated with lithium carbonate the study was showed that the decrease in sperm motility (℅), viability, life sperm % and sperm abnormal %were significant at the level of (P≤ 0.05). The motility (℅), viability and life sperm % were significant increase at the level of (P≤ 0.05).
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