Background: Tuberculosis is associated with various haematological abnormalities of varying severity and improvement of which is dependent only on the improvement of disease process with initiation of the treatment. This study aims at prospective study of various haematalogical manifestations in sputum positive pulmonary tuberculosis and during the course of treatment.
Methodology: 100 cases of sputum positive pulmonary tuberculosis cases admitted and registered at RNTCP center, were selected from random sampling.
New sputum positive cases and relapse cases aged between 15-65 years were included and patient who are already on anti-tubercular treatment, other comorbid diseases altering the disease process were excluded. Detailed history, habits of smoking and alcohol and detailed examination were done according to proforma and was followed up till the period of 6 months.
Results: Of the 100 patient 71% were male and 29% female. Prevalence of anemia in our study was 89%, mild to moderate anemia was seen in 87% and severe anemia in2% with male being more affected than female patients. Peripheral blood smear showing 74% was normocytic normochromic picture 3%was microcytic picture, 11% was macrocytic peripheral picture and 12% was dimorphic picture.Conclusion: Sputum positive pulmonary tuberculosis is associated with various haematological manifestation. This haematological abnormalities reversed during treatment, follow up improving the patients quality of life.