The dyslipoproteinemia seems to result primarily from abnormalities in the transport and metabolism of triglyceride rich lipoprotein. The pathogenic links between the progressive decrease in renal function and the development of lipoprotein abnormalities are still poorly understood. Patients presenting to the hospital and diagnosed with CKD were included in the study after obtaining informed consent until sixty cases were collected. The history of the onset, progression, duration of various symptoms, drug and diet history was noted. Laboratory investigations like basic blood profile, blood urea, serum creatinine, serum cholesterol, serum triglyceride, serum LDL, serum HDL, Lp(a) and ultrasound abdomen was done. The mean value of Serum Triglycerides is 159.76 mg/dl, Serum cholesterol is 184.17 mg/dl, Serum HDL is 41.8 mg/dl, Serum LDL is 111.37 mg/dl, Serum VLDL is 31.1 mg/dl and lipoprotein (a) is 39.26mg/dl.