International Journal of Medicine Research

International Journal of Medicine Research


International Journal of Medicine Research
International Journal of Medicine Research
Vol. 1, Issue 3 (2016)

A comparison of effect of oral premedication with clonidine and Metoprolol on intraoperative hemodynamics and surgical conditions during functional endoscopic sinus surgery


Dr. Pratiti Gohil, Dr. Malti J. Pandya, Dr. Pooja Patwa

AIM: The present study was done to compare the effect of oral premedication with clonidine and Metoprolol on intraoperative hemodynamics and surgical conditions during Functional endoscopic sinus surgery. Material and Methods: 42 patients of ASA I & II 18-60 years posted for FESS were randomly divided into two groups of 21 each. All patients received tab. diazepam 10 mg and clonidine 300 µg in group A and tab. diazepam 10 mg and metoprolol 50 mg in group B 2 hour before induction. HR, BP recorded intra & postoperatively. The quality of surgical field was assessed and graded by surgeon according to the ACS. Total blood loss, duration of surgery and adverse effect were noted. Results: Bleeding severity score were lower in group A than group B. There was less bleeding volume in group A (156.9±33.71) than in group B (179.3±33.63). The HR decreases significantly from pre induction to up to 90 minutes in group B as compared to group A (p<0.001). After 30 minutes of induction SBP was significantly lower in group A compared to group B till extubation. Conclusion: Premedication with clonidine provides less bleeding, better quality of surgical field and stable hemodynamics in patients undergoing FESS.
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How to cite this article:
Dr. Pratiti Gohil, Dr. Malti J. Pandya, Dr. Pooja Patwa. A comparison of effect of oral premedication with clonidine and Metoprolol on intraoperative hemodynamics and surgical conditions during functional endoscopic sinus surgery. International Journal of Medicine Research, Volume 1, Issue 3, 2016, Pages 04-06
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