A study on lipid Profile of old aged patients of dyslipidemia with and without type 2 Diabetes mellitus: A hospital based observational study
Dr. Nandani, Dr. Abhay, Dr. Nipendra Kishore, Dr. Ajay Khanna
Aims: aim of our study was to evaluate the lipid profile of old aged dyslipidemic patients with and without type 2 diabetes mellitus.
Methods: A detail history, clinical examination and relevant investigations were performed all patients. Plasma glucose estimation was performed by using RFCL kit on the microlab -300 Semi Auto- analyzer supplied by Merck. Total cholesterol was estimated quantitatively by CHOD-PAP technique. Serum Triacylglycerol was estimated quantitatively by GPO-ESPAS technique.
High density lipoproteins (HDL-C) was estimated quantitatively by PEG-PAP method.
Very low density lipoproteins (VLDL-C) was estimated from serum triacylglycerol level using Friedewald formula and low density lipoproteins (LDL-C) was calculated by subtracting serum HDL and VLDL from total serum cholesterol.
Results: Data was analyzed by SPSS software. Mean ± S.D and Person’s r value were observed. P value was taken ≤ 0.05 for significant differences.
Conclusions: Old age as well as diabetic state both were affected the lipid profile. All constituent of lipid profile had an increasing trend with age and diabetes except HDL which had a negative trend with advancing age. Hence, diabetes mellitus accelerates age related disturbances in lipid profile.