International Journal of Medicine Research


ISSN: 2455-7404

Vol. 3, Issue 3 (2018)

Comparative evaluation of effect of Ondansetron and Ondansetron with dexamethasone for prevention of nausea, vomiting & shivering in patient of caesarean section under spinal Anesthesia

Author(s): Dr. Nipa N Desai, Dr. Smitul Dave, Dr. Nirupama Sunasara, Dr. Nirav Prajapati
Abstract: Background: Nausea and vomiting after cesarean section is reported in more than 66% of cases due to sudden contraction in diaphragm and manupulation and stretching of abdominal viscera. Similarly due to redistribution of blood flow shivering occurs in spinal anaesthesia. Nausea and vomiting resulted in different problems such as delayed discharging from post anesthesia care unit, high length of hospital stay, high risk of aspiration, and serious problems. Objectives: This study aims at evaluating the efficacy of Ondansetron and Ondansetron with Dexamethsone for prevention of nausea, vomiting & shivering in patient of caesarean section under spinal anesthesia Materials and Methods: Total 100 patients of age group 18to 35 years of ASA grade I /II were selected. Patients were randomly divided into two groups (n=50). In Group O inj. Ondansetron {4mg} and in Group OD inj. Ondansetron 4mg + inj. Dexamethasone 8mg was given. During the post-delivery period, nausea, vomiting and shivering episodes were recorded. Results: There was significant difference in the incidence of nausea and vomiting between the groups (p value= 0.027). Conclusion: Our study concluded that combined use of ondansetron 4mg and dexamethasone 8mg is effective in controlling PONV in CS after spinal anesthesia as compared to ondansetron 4 mg alone.
Pages: 19-21  |  867 Views  273 Downloads
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