The study of association of stroke in human immunodeficiency virus infected patients
Vilas Honnakatti, Giridhar Patil
Introduction: Stroke in HIV is increasing in the developed countries from the data & studies. To say HIV infection as one of the risk factor for stroke is not known and the mechanism still being unclear. HIV is an emerging etiology for stroke in the young, particularly in a population with high seroprevalence for retroviruses. Studies reveal that the stroke in HIV patients is increasing even in the general population from stroke data. Material and methods: The cross sectional study was conducted in the Department of General Medicine, Belagavi Institute of Medical Sciences Belagavi, India. Twenty HIV infected patients fulfilling inclusion criteria, were included and a detailed history of mode of transmission of HIV, risk factors, Laboratory investigation findings was noted. Results: Twenty HIV infected stroke patients were included in the study, 12 were males & 8 were females.The mean age at presentation was 41.15 with SD 13.05565. Patients had risk factors like age, menopause, alcohol, diabetic, smoking, dyslipidemia. Seventy five percent females had menopause as risk factors and 30% patients had dyslipidemia as risk factor. Forty five percent patients were presented during initial 1 year after HIV infected status and 25% patients were presented 1-2 year after HIV infection. The median CD4 counts at presentation was 139. Conclusion: HIV infection is one of the risk factor for the occurrence of stroke in young population, due to exposure to opportunistic infections. Chronic inflammation due to HIV infection results in a prothrombotic state. HIV/ART-induced dyslipidemia may lead to etiopathogenesis for stroke.