Socio-cultural behavior comparative study of the misuse of Cyproheptadine combined with Dexamethasone in Kinshasa population, Democratic Republic of Congo
Mputu Malolo LC, Ndelo Matondo P, Nuapia BELO Y, Mwelo Ngobe JA, Pandi Binda D, Z Sita ZA, Ndelo-di-Phanzu J
Objective: The aim of this study is to determine the prevalence of Cyproheptadine combined with dexamethasone misuse in two groups of the Kinshasa population and to describe its characteristics. Methods: A cross-sectional study was conducted in two town sectors of Kinshasa (N’djili city and University of Kinshasa), Democratic Republic of Congo (DRC), over a 4 month period (September 2012 to December 2012). Data from 305 participants, aged between 18 and 30 years were collected and analyzed. Mean and standard deviation were used for quantitative variables and frequency and percentage for categorical variables. In order to determine the relationship between sociodemographic status and Cyproheptadine combined with dexamethasone use the Chi-square test was conducted. Logistic regression was used to determine predictors of Cyproheptadine combined with dexamethasone use. A p-value of <0.05 was considered statistically significant. Results: A total of 315 females were enrolled in the study, the response rate were 96.82% (305 participants). There were 199 participants from N’djili city (77.22 %) with 139 users of cyproheptadine combined with dexamethasone and 106 participants from University of Kinshasa (22.78 %) with 41 users of cyproheptadine combined with dexamethasone. The major of participants had a range of age between 18-22 years old in University of Kinshasa (46.34%) and between 23-26 years old in N’djili city (46.04%). the main reason for Cyproheptadine combined with dexamethasone use in N’djili city was to have buttock’s while to become beautiful was the main reason of use in the University of Kinshasa (71.00%). Self-prescription was the most common procurement method (98.56 % in N’djili city and 95.12% at University of Kinshasa). The misuse of Cyproheptadine combined with dexamethasone was significantly associated with site, N’djili city (69.8 %) used more Cyproheptadine combined with dexamethasone than Students of the University of Kinshasa (38.68 %) (Chi - square = 79.13, df = 1; p=0.0001). Conclusion: This study shows that the Kinshasa population is significantly misusing Cyproheptadine combined with dexamethasone either to have buttock’s protuberances or to become beautiful and is highly exposed to its risk, including obesity and infertility.