The purpose of this study was to identify the relationship between the quality of life of patients with a diagnosis of paranoid schizophrenia and the type of pharmacotherapy. Objectives of the study: 1. Measurement of the quality of life of patients; 2. Determination of the correlation coefficient between the age of patients and the quality of life indicator. The study was conducted by questioning the patients on the basis of the State Budgetary Healthcare Institution Psychiatric Hospital No 5 of Krasnodar region. The study involved 65 patients. The questioning was carried out using the questionnaire "Assessment of the quality of life of patients with schizophrenia during maintenance therapy", developed by the St. Petersburg Psychoneurological Institute named after Bekhterev of the Ministry of Health and Social Development of the Russian Federation. Significant positive correlations were finally found between the quality of life of patients and the antipsychotics of the 2nd generation usage. Also, we saw a negative correlation between the age of patients and the value of the quality of life index.