Vol. 1, Issue 3 (2016)
A comparison of effect of oral premedication with clonidine and Metoprolol on intraoperative hemodynamics and surgical conditions during functional endoscopic sinus surgery
Author(s): Dr. Pratiti Gohil, Dr. Malti J. Pandya, Dr. Pooja Patwa
Abstract: AIM: The present study was done to compare the effect of oral premedication with clonidine and Metoprolol on intraoperative hemodynamics and surgical conditions during Functional endoscopic sinus surgery. Material and Methods: 42 patients of ASA I & II 18-60 years posted for FESS were randomly divided into two groups of 21 each. All patients received tab. diazepam 10 mg and clonidine 300 µg in group A and tab. diazepam 10 mg and metoprolol 50 mg in group B 2 hour before induction. HR, BP recorded intra & postoperatively. The quality of surgical field was assessed and graded by surgeon according to the ACS. Total blood loss, duration of surgery and adverse effect were noted. Results: Bleeding severity score were lower in group A than group B. There was less bleeding volume in group A (156.9±33.71) than in group B (179.3±33.63). The HR decreases significantly from pre induction to up to 90 minutes in group B as compared to group A (p<0.001). After 30 minutes of induction SBP was significantly lower in group A compared to group B till extubation. Conclusion: Premedication with clonidine provides less bleeding, better quality of surgical field and stable hemodynamics in patients undergoing FESS.
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