Vol. 1, Issue 1 (2016)
Pharmacovigilance study on the different drugs used for the management of conjunctivitis in Bangladesh
Author(s): Most. Rawsanara Bakchi, Md. Ashrafudoulla, Farhan Fuad, Md. Raisul Islam Rubel, Md. Siddiqul Islam, Md. Habibur Rahman, Salma Parvin
Abstract: At present, pharmacovigilance (PV) study is one of the key ways to improve and ensure drug safety and patient’s health care in the whole world including Bangladesh. Very limited systematic studies have been conducted on PV in Bangladesh. The overall purpose of this study was to assess treatments of conjunctivitis patients in Bangladesh. Both primary and secondary data were collected for this study from two different hospitals in Dhaka, Bangladesh. Result shows that, the number of drugs used in conjunctivitic patients were moxifloxacin (30%), olopatadine (10%), fluorometholone+ gentamicin (10%), hypromellose (5%), ketotifen (10%), rupatadine (20%), dexamethasone + tobramycin (10%), flunarizine (5%). There was different adverse drug reactions (ADRs) like blurred vision, redness of eye, itching eye, burning of eye, pain in eye, tearing, swelling of eye, hypersensitivity. Among 210 patients, 25 patients were found to be affected with blurred vision (12%), 20 patients with redness of eye (10%), 20 patients itching eye 10%, 15 patients burning of eye (7%), 10 patients pain in eye (5%), 5 patients tearing (3%), 5 patients swelling of eye (3%) and 2 patients hypersensitivity (1%) etc. In this study we have found that moxifloxacin (30%) was most frequently prescribed antibiotic and rupatidine (20%) was most common antihistamine. The commonly observed ADR were blurred vision and redness of eye.